Lipid class

Phosphatidylethanolamine

Description
placeholder: The phosphatidylethanolamine (PE) class of lipids is a subtype of phospholipids, comprising a glycerol backbone esterified with two fatty acid chains and a phosphoethanolamine headgroup. The fatty acid tails, typically unsaturated, are inserted into the hydrophobic core of membranes, while the phosphoethanolamine headgroup, bearing a net negative charge, interacts with the aqueous environment. This amphipathic structure enables PE molecules to form bilayers, a crucial component of biological membranes. Functionally, PE lipids play a key role in maintaining membrane fluidity, curvature, and fusion, as well as modulating protein-lipid interactions. In particular, PE has been implicated in the regulation of membrane-bound enzyme activity, vesicle trafficking, and apoptosis. Additionally, PE is a precursor to other lipid species, such as phosphatidylcholine, and its metabolism is intertwined with various cellular processes, including signal transduction and membrane remodeling.
Example 2D structure
An example of the Phosphatidylethanolamine (34:1) species (C39H76NO8P).
Image of the 2D molecular structure of an example member of the Phosphatidylethanolamine lipid class. Image of the 2D molecular structure of an example member of the Phosphatidylethanolamine lipid class.
Phosphatidylethanolamine class lipid.
Roll over the image for an enlargement.
Phosphatidylethanolamine lipid species
Sorted by: molecular weight
Molecular formula Lipid species Molecular weight (g/mol) "Isoform specificity"
CD1a CD1b CD1c CD1d
C39H76NO8P Phosphatidylethanolamine (34:1) 718.54
C41H78NO8P Phosphatidylethanolamine (36:2) 744.55
C43H76NO8P Phosphatidylethanolamine (38:5) 766.54
C43H78NO8P Phosphatidylethanolamine (38:4) 768.55
C45H76NO8P Phosphatidylethanolamine (40:7) 790.54
C47H90NO8P Phosphatidylethanolamine (42:2) 828.65
C47H92NO8P Phosphatidylethanolamine (42:1) 830.66
C49H94NO8P Phosphatidylethanolamine (44:2) 856.68
C49H96NO8P Phosphatidylethanolamine (44:1) 858.69
placeholder: Only lipid species which could be unambigously determined experimentally are shown.

DEBUG INFO